Centered around an ultralounge that looks like aPicture 10 futuristic parlor—all mirrors and chandeliers, in shades of black, white, yellow, orange, Lucite, and chrome—5 Degrees aims to be as cool as its name. So does the flirty LoDo crowd, who dresses to kill before settling into wraparound booths and splurging on bottle service, mingling out on the patio, or meeting face-to-face on the small, tightly packed dance floor.

Special events are a club hallmark—from fashion shows and photo shoots to Whipped Wednesdays, as the often-themed ladies’ night is called (a recent, cheeky example: Barbie’s Birthday). In sum: keep the footwork to a minimum, the ogling to a maximum, and you’ll fit right in.